Monoamines (also known as brain chemicals or neurotransmitters) such as dopamine, serotonin, noradrenaline play important roles in our body’s central nervous system and are involved in a wide range of physiological and homeostatic functions.
Dopamine is important in the regulation of movement, cognitive processes such as attention and working memory and modulating behaviour.
Noradrenaline is an important driver of the sympathetic nervous system and is involved in cardiovascular function, arousal, concentration, attention, learning and memory.
Serotonin is an important driver of the parasympathetic nervous system and is also present in our platelets and gastrointestinal mucosa. It is involved in regulating blood pressure and complex behaviours including mood, appetite, sleep, cognition, perception, motor activity, temperature regulation, pain control, hormone secretion.
Changes in stress on the body can affect our nutrient intake requirement that diet alone can no longer supply, which is needed to maintain optimum homeostatic and physiological function. This is referred to as a relative nutritional deficiency and can be partially responsible for depleted monoamines or brain chemicals. Chronic depleted monoamines can cause neuron damage in our central nervous system and lead to a range of mood, cognitive, motor, and motor deficits .
Syndromes and disorders related to these central nervous system monoamine neurotransmitters can included:
If you or a family member are experiencing any symptoms or disorders mentioned above, get in contact with one of our Doctors so we can explore further management options for you.
 Tzschentke, T. M. (2001). Pharmacology and behavioral pharmacology of the mesocortical dopamine system. Progress in Neurobiology, 63(3), 241–320.
 Ressler, K. J. & Nemeroff, C. B. (1999). Role of norepinephrine in the pathophysiology and treatment of mood disorders. Biological Psychiatry, 46(9), 1219–1233.
 Saxena, P. R. (1995). Serotonin receptors: subtypes, functional responses and therapeutic relevance. Pharmacology and Therapeutics, 66(2), 339–368.
 Hinz, M., Stein, A., & Uncini, T. (2012). Relative nutritional deficiencies associated with centrally acting monoamines. International journal of general medicine, 5, 413.
The Drs and Staff of Little Sprouts Chiropractic